What are you waiting for? The Department of Rheumatology and Clinical Immunology and Center for Chronic Immunodeficiency, in the group of Prof. Dr. Marta Rizzi, is looking for you are available as per February 1st, 2024
PostDoc position immunology (m/f/d)
The projects require both wet-lab and bioinformatics analysis. Our group studies human B-lymphocytes development, maturation and activation in physiological and pathological conditions. Our lab has unique expertise in in-vitro modelling of early and late human B cell development that we use: to uncover mechanisms of disease in monogenic defects leading to autoimmunity; to study the B cell function in more complex rheumatological diseases; to assess the specific impact on human B lymphocytes of novel targeted therapies. (https://www.uniklinik-freiburg.de/rheuim/wissenschaft-und-forschung/ag-rizzi.html).
The research focuses of the position will be: single cell analysis of developmental pathways in early and late B cell development; B cell repertoire analysis, development of 3D culture systems to model development and cell-cell interactions, integration and outcome of signaling in B cells.
We offer:
- work at the interface of translational medicine and basic research
- a well-equipped, state-of-the-art research environment within the University Medical Center Freiburg
- a large international network of collaborators and interdisciplinary projects
- the opportunity to learn and apply a variety of modern methods in cell-, protein- and molecular biology
- an enjoyable laboratory atmosphere with intensive mentorship
- Involvement in student teaching and mentoring
Required skills:
- Ph.D. in biology or in a related field with an excellent publication record OR
- PhD in computer science, mathematics, physics, bioinformatics, computational biology or similar background with focus on bioinformatics or data science. Alternatively, a M.Sc. or equivalent qualification with complementary years of relevant experience.
- hands-on experience with workflow development and -omics data (single cell RNA seq, transcriptomics, B cell receptor repertoire) analysis using open source software and algorithms
- Experience in state-of-the-art molecular biology and/or biochemistry
- Experience in working with primary human cells and cell lines (isolation, cultivation, stimulation, 3D cultures)
- creative innovative thinking
- intrinsic motivation, high precision of work and the ability to conduct independent research
- Interest in working in an interdisciplinary environment
- proven English presenting and writing skills
The position is limited to 36months.
Please send applications including the usual documentation via the "Apply Now" button.
For further inquiries, please contact:
Prof. Marta Rizzi - Group Leader
+49-761/270-62170
