BRAINET (www.brainet-dn.eu) has received funding from the European Union’s Horizon Europe research and innovation program under the MARIE SKŁODOWSKA-CURIE grant agreement no 101225775.
Research areas:
DC 13: Pre-clinical validation of temporal interference stimulation with a Parkinsonian rat model
Terms:
The position is limited to 36 months. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz – WissZeitVG).
Supervisory team:
Supervisor: Prof. Dr. Ulrich Hofmann, Co-Supervisor: Prof. Jari Hyttinen (TAU) and Prof. Filipe Vaz (UMINHO)
Secondment:
3 months with Tampere University, Finland and 3 months with MED-EL Innsbruck, Austria.
About BRAINET:
The BRAINET consortium tries to augment DBS with spatio-temporal Interference Stimulation (stIS). We will beneficially influence therapeutic regions deep in the brain without requiring deep seated electrodes. BRAINET sets out to develop skull implantable stimulation hubs forming a communication network for 3D targeting by self-organization, providing semantic information transfer and synchronization, and thus enabling self- adjusting therapeutic stIS. These stimulation hubs will be powered by novel magneto-electrical transducer stacks, driven by slowly alternating magnetic fields from the outside and will perform adjustable frequency stimulation by novel nano-modified, compliant electrodes only touching the brain. Network formation will be enabled by multiphysics approaches and ionic in-body communication instantiated by dedicated microelectronic hardware. Preclinical in-vitro and in-vivo testing of devices and methods will allow real world validation of this unusual Brain-Computer Interface (BCI).
The advertised position will be one of 14 throughout Europe (doi:10.3030/101225775), salary according to MSCA regulation.
The doctoral candidate will investigate non-invasive interference stimulation with a rat model of Parkinson’s Disease (doi:10.3389/fnins.2020.561008). Handling animals in a professional way will be required. It will be in the DC’s hands to rigorously characterize and describe behavioral consequences, dose-effect curves and histological changes following interference stimulation as compared to Deep Brain Stimulation (doi:10.3389/fnins.2021.700672).